王非
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邮箱：wangfeirj@163.com; wf11878@rjh.com.cn;
王非，博士，副研究员，2015年毕业于华东师范大学，同年入职上海交通大学医学院附属瑞金医院/上海市伤骨科研究所，生物医学工程中心-核酸药物递送技术课题组长。从事基因载体优化及智能化核酸药物递送系统在运动系统疾病中的防治研究。已在Adv Mater, Sci Adv, Adv Funct Mater, Biomaterials等期刊发表论文50余篇，累计引用2500余次，H指数为28，授权专利5项，国际书籍1章。主持国家自然基金、上海市科委基金、上海市卫健委等多项课题。获上海市卫生健康人才计划、上海市医学科技奖、瑞金医院最佳发展团队、广慈卓越青年等；任国际华人骨研学会(ICMRS)会员、中国生物材料学会-康复器械与生物材料，中国康复医学会修复重建外科、中国中西医结合学会骨伤科分会委员等。
课题项目：
1. 国自然青年项目（21604052），主持
2. 上海市卫生健康青年人才（2022YQ073），主持
3. 上海市自然基金面上项目（20ZR1450600），主持
4. 上海市卫健委科研课题（20164Y0179），主持
5. 瑞金医院广慈卓越青年（GCQN-2018-A13），主持
6. 国家重点研发计划青年项目（2019YFA0112000），骨干
7. 国家重点研发计划（2022YFA1304304），骨干
代表性论文（通讯作者和一作）：
1.S Wang#, Y Xiao#, J Tian, B Dai, Z Tao, J Liu, Z Sun, X Liu, Y Li, G Zhao, Y Cui, F Wang*, S Liu*. Targeted Macrophage CRISPR-Cas13 mRNA Editing in Immunotherapy for Tendon Injury. Adv Mater, 2024, e2311964.
2.J Liu, L Chen, Z Sun, Z Tao, V Pavel, Y Li, F Wang*, W Cui*, S Liu*. Unidirectional gene delivery electrospun fibrous membrane via charge repulsion for tendon repair. Bioact Mater. 2024, 37:191–205.
3.H Chen#, Fjing Chen#, F Hu, Y Li, M Zhang, Q Zhou, T Ding, N Tulufu, T Ye, F Wang*, LGuo*. MicroRNA-224-5p nanoparticles balance homeostasis via inhibiting cartilage degeneration and synovial inflammation for synergistic alleviation of osteoarthritis. Acta Biomater. 2023,167:401-415.
4.C Cai#, X Zhang#, Y Li, X Liu, S Wang, M Lu, X Yan, L Deng, S Liu*, F Wang*, C Fan*. Self-healing Hydrogel Embodied with Macrophage-regulation and Responsive-gene-silencing Properties for Synergistic Prevention of Peritendinous Adhesion. Adv Mater, 2022, 34(5):2106564.
5.C Cai#, W Wang#, J Liang, Y Li, M Lu, W Cui, C Fan, L Deng, Y Li, F Wang*, S Liu*. MMP-2 Responsive Unidirectional Hydrogel-Electrospun Patch Loading TGF-β1 siRNA Polyplexes for Peritendinous Anti-Adhesion. Adv Funct Mater. 2021, 31(6):2008364.
6.B Li#, F Wang#, F Hu, T Ding, P Huang, X Xu, J Liang, C Li, Q Zhou, M Lu, L Deng, L Guo*, W Cui*. Injectable “nano-micron” combined gene-hydrogel microspheres for local treatment of osteoarthritis. NPG Asia Mater, 2022, 14:1.
7.K Chen#, F Wang#, R #, Z Cai, T Zou, A Zhang, D Guo, B Ye*, W Cui*, M Xiang*. Adhesive and Injectable Hydrogel Microspheres for Inner Ear Treatment. Small, 2022, 2106591.
8.F Wang, K Hu, Y Cheng*, Structure-activity relationship of dendrimers engineered with twenty common amino acids in gene delivery. Acta Biomater, 2016, 29(1):94-102. IF=9.7
9.F Wang, L Deng, J, Yiyun Cheng*, Being Two Is Better than Being One: A Facile Strategy to Fabricate Multicomponent Nanoparticles for Efficient Gene Delivery. Bioconjugate Chem, 2016, 27(3):638-646.
10.F Wang, Y Wang, H Wang, N Shao, Y Chen, Y Cheng*, Synergistic effect of amino acids modified on dendrimer surface in gene delivery. Biomaterials, 2014, 35(33):9187-9198.
论著：
1.Fei Wang, Lianfu Deng and Wenguo Cui. The Improved Strategies of Dendrimers as Gene Vectors. Emerging Technologies in Biophysical Sciences: A World Scientific Reference. Chapter 15. (2023) pp. 435-472
荣誉奖项：
1.上海市卫生健康青年人才
2.上海市医学科技奖青年奖
3.瑞金医院最佳发展团队
4.瑞金医院广慈卓越青年
5.上海市骨科年会优秀论文奖
6.上海市优秀毕业生
地址：上海市瑞金二路197号 电话：021-64313534
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