裴明亮
裴明亮,博士,助理研究员,2020年毕业于兰州大学化学化工学院,并获得博士学位。2020-2023年于同济大学医学院进行博士后研究。主要从事响应性纳米诊疗制剂的设计和生物效应评价相关研究,围绕响应性纳米递药和荧光探针“开-关”等关键科学问题,开展了系列的“智能”响应型纳米制剂的构建,实现可控药物释放和有效制剂体内追踪,为开发新型高效药物制剂奠定基础。基于上述研究成果,在Carbohydr. Polym.、Mater. Des.、J. Mater. Chem. B、Mater. Sci. Eng. CMol. Pharmaceutics权威期刊发表20余篇SCI论文,一作SCI论文12篇,授权专利3项。主持中国博士后科学基金面上资助和上海市“超级博士后”激励计划,多次参与国家自然科学基金面上项目。

一、代表性论文:
1.Manxiu Huai#, Mingliang Pei#,*, Jiaxing Pan, Yun Zhu, Yingwen Chen, Peng Du, Yanming Duan, Huixiong Xu*, Wensong Ge*, Oral colon-targeted responsive alginate/hyaluronic acid-based hydrogel propels the application of infliximab in colitis. International Journal of Biological Macromolecules, 2023, 249, 125952. 2.Mingliang Pei, Xu Jia, Xubo Zhao, Jiagen Li, Peng Liu, Alginate-based cancer-associated, stimuli-driven and turn-on theranostic prodrug nanogel for cancer detection and treatment, Carbohydrate Polymers. 2018, 183, 131-139. 3.Mingliang Pei, Guoping Li, Peng Liu, Tumor-specific fluorescent Cdots-based nanotheranostics by acid-labile conjugation of doxorubicin onto reduction-cleavable Cdots-based nanoclusters. Materials Science and Engineering: C, 2020, 110, 110719. 4.Mingliang Pei, Xu Jia, Peng Liu, Design of Janus-like PMMA-PEG-FA grafted fluorescent carbon dots and their nanoassemblies for leakage-free tumor theranostic application. Materials & Design, 2018, 155, 288-296. 5.Mingliang Pei, Changou Pan, Peng Liu, Facile fabrication of superhydrophobic surface with palygorskite-poly(2-(perfluorohexyl)ethyl methacrylate) composite microgels. Composites Communications, 2021, 25, 100740. 6.Mingliang Pei, Xu Jia, Guoping Li, and Peng Liu*, Versatile polymeric microspheres with tumor microenvironment bioreducible degradation, pH-activated surface charge reversal, pH-triggered“off-on”fluorescence and drug release as theranostic nanoplatforms. Molecular Pharmaceutics, 2019, 16(1), 227-237. 7.Mingliang Pei, Jui-Yu Pai, Pengcheng Du, and Peng Liu*, Facile synthesis of fluorescent hyper-cross-linked β-cyclodextrin-carbon quantum dot hybrid nanosponges for tumor theranostic application with enhanced antitumor efficacy. Molecular Pharmaceutics, 2018, 15(9), 4084-4091. 8.Mingliang Pei, Xiaomei Zhao, Guoping Li, Wei Chen, Peng Liu, Fluorescent turn-on carbon dot-cored pseudo unimolecular prodrug micelles for tumor-specific dual-triggered drug delivery. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2021, 620, 126490. 9.Mingliang Pei, Changou Pan, Dan Wu, Peng Liu, Surface hydrophilic-hydrophobic reversal coatings of polydimethylsiloxane-palygorskite nanosponges, Applied Clay Science, 2020, 189, 105546. 10.Mingliang Pei, Guoping Li, Kangwei Ma, Jianan Li, Yuanfan Wang, Peng Liu, Polymeric prodrug microspheres with tumor intracellular microenvironment bioreducible degradation, pH-triggered “off-on” fluorescence and drug release for precise imaging-guided diagnosis and chemotherapy, Colloids and Surfaces B: Biointerfaces, 2019, 177, 313-320.

二、联系方式: 电子邮箱:pei1991@sjtu.edu.cn. 通讯地址:上海市闵行区上海交通大学唐仲英楼E317室
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